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Bilirubin Bilirubin is found in all red-blooded animals. It is a natural by-product of the breakdown of hemoglobin, itself a by-product of normal red blood cell turnover. It is metabolized in the liver and is the principle pigment in bile. The normally
functioning liver removes bilirubin from the blood and reincorporates it into
bile stored in the gall bladder. In the malfunctioning liver this function may
be impaired causing higher than normal levels of bilirubin in the blood stream
(serum bilirubin). Liver function tests
commonly use diagnostic bilirubin as a standard preparation to compare with
serum bilirubin levels and measure liver function. In recent years
several studies on the biochemical properties of bilirubin present strong
evidence that the compound plays a beneficial role in the body, particularly as
an endogenous (naturally generated within the body) antioxidant. Antioxidants
are part of the human bodies natural defense system, which operates to scavenge
and quench destructive oxygen radicals. The
in vitro antioxidant properties of bilirubin were delineated
largely by Stocker and co-workers in the late 1980’s. Bilirubin
supplementation provides health benefit to persons at risk of heart attack
including smokers. Bilirubin has been shown reduce the oxidation of Low Density
Lipoprotein (LDL), which has been implicated in plaque formation within blood
vessels leading to heart disease. Frei et al found that bilirubin was
more effective than other endogenous antioxidants, at protecting lipids from
peroxyl radicals. A recent United States study examined the association between
cigarette smokers and serum bilirubin antioxidant concentration. The study shoved that smoking is associated
with a decrease in serum bilirubin concentration. This decrease in serum
bilirubin may be associated with an increased incidence of heart attack in
smokers. Bilirubin sold in
four different forms such as
Bio Pharma Pty
Ltd, extract and purify commercial quantities of bilirubin from cattle and pig
bile. Bulk bilirubin will be sold in
0.5kg, 1kg and 2kg dark plastic airtight and security sealed containers.
Biliverdin is a new product on our list and will be available very soon. Please ask for specification.
P.O.Box 194, Coopers Plains QLD 4108
Australia |