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Bile Acids
Bile acids are the
end product of cholesterol utilization in the liver of vertebrates.
Bile acids are produced in the liver,
stored in the gall bladder and secreted into the gut to aid the absorption of
dietary fats. A large percentage of these bile acids are reabsorbed by the gut
and returned to the liver via the blood.
Bile acids are
essential for the digestion and absorption of lipids (fats) and lipid soluble
vitamins. They are the major regulators of cholesterol production and
cholesterol extraction in humans. They are also potential carriers of liver
specific drugs and new cholesterol-lowering agents.
Cholic acid is a naturally occurring
human bile acid. It is extracted commercially from cattle bile.
The primary commercial use of cholic acid
is as an intermediate in the synthesis of ursodeoxycholic acid (UDCA), which is
a pharmaceutical product used for the dissolution of gallstones and the
prevention and treatment of liver diseases.
Cholic acid is also used in traditional
Asian medicine and it is one of the ingredients used to formulate Artificial
Bezoar.
Cholic acid is
delivered in sealed polyethylene bags packed in 25kg fibre drums.
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Chenodeoxycholic Acid (CDCA) is a naturally occurring human bile acid. It
can be produced synthetically from cholic acid or purified from pig bile. CDCA
is also used as an intermediate in the production of UDCA. Both CDCA and UDCA
are active pharmaceuticals, which assist in the dissolution and prevention of
cholesterol gallstones in humans.
Chenodeoxycholic acid is delivered in
sealed polyethylene bags packed in 25kg fibre drums.
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Hyodeoxycholic Acid (HDCA) is a naturally occurring human and pig bile acid. HDCA is used as
an intermediate in the production of
steroid drugs.
Bio Pharma Pty
Ltd. has developed a new method for the recovery of HDCA, which yields a 99%+
product from pig bile.
Hyodeoxycholic acid
is delivered in sealed polyethylene bags packed in 25kg fibre
drums.
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Deoxycholic Acid (DCA) is a naturally occurring human bile acid. It is
extracted commercially from cattle and sheep bile. DCA is used as an ingredient
in pharmaceutical formulations, artificial bezoar and other Asian medicine
formulations. DCA is also used as a biological detergent.
Deoxycholic acid is delivered in sealed
polyethylene bags packed in 25kg fibre drums.
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P.O.Box 194, Coopers Plains QLD 4108
Australia
Ph: +61 7 3277 6547 Fax: +61 7 3277 6542
E-mail: office@biopharma.com.au
